Flexible, Responsive Capital

R. Bryan Jadot is Head of Life Sciences Venture Lending and brings over 32 years of financial and credit structuring experience to Hercules.

Prior to joining Hercules in 2005, Jadot served as vice president of the Life Sciences Group at Silicon Valley Bank (SVB) in Newton, MA where he co-managed a banking group dedicated to New England-based life science clients including biotechnology, medical device, and healthcare IT clients. Jadot also worked as the vice president of the Software Group at Silicon Valley Bank in Palo Alto, CA.

Prior to Silicon Valley Bank, Jadot worked with the Corporate Banking arm of the Banque Nationale de Paris (BNP) in San Francisco, CA and was an assistant economist with the Department of Treasury’s Office of Eastern Europe and former Soviet Union in Washington DC.

Jadot earned a B.A. in economics and government from California State University at Sacramento, and completed the Wells Fargo Bank Credit Management Training Program. He served as a nuclear operations specialist with the US Army (Europe) and is fluent in French.

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Mike Dutra is a Senior Managing Director and Senior Investment Officer in the Life Sciences Group working in the Boston office. He is focused on transactions with a broad range of private and public healthcare companies including biotechnology, specialty pharmaceuticals, medical device, innovative services, and other healthcare companies at all stages of development. Mike joined Hercules in June 2014 and was most recently promoted to Managing Director in January 2021. Prior to Hercules, he held positions with Goldman Sachs as an Operations Analyst and with DePuy Synthes as a Quality Engineer. Mike graduated with honors from Northeastern University with a B.S. in Industrial Engineering.  

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Lake McGuire is Managing Director responsible for business development in the life sciences and broader healthcare market. He is a seasoned executive, with more than 19 years of experience in the middle-market and venture debt markets, focused on structuring financial transactions for life sciences and technology related companies. Most recently, Mr. McGuire served as Vice President, Business Development at Comerica Bank, and was responsible for business development in the life sciences and technology markets. He has served in various roles in the Technology and Life Sciences and the Middle-Market Divisions during his 10-year tenure at Comerica Bank. Mr. McGuire received a Bachelor of Science in Construction Management from Michigan State University and a Master of Business Administration in Finance from the University of Michigan.

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Cristy Barnes is a Managing Director in Hercules’ Life Sciences Group. Cristy brings to Hercules over 26 years of investing experience working in both the private and public equity markets.

Most recently, Cristy served as Managing Director at Lighthouse Capital Partners, a leading venture debt firm, where she led the fund’s healthcare efforts, focusing primarily on VC-backed biotech and medical device opportunities. While at Lighthouse, Cristy sourced, structured and negotiated 70 loan transactions providing $455 million in commitments to promising growth-oriented businesses.

Prior to joining Lighthouse, Cristy was a Senior Associate at Highland Capital Partners, where she worked on west coast technology venture capital investments.  Before Highland, Cristy spent five years at Robertson Stephens and Company in the Technology Research Group.

Cristy holds a BA in Psychology with a minor in Business from the University of California, Los Angeles.

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Michael Bowden is a Managing Director, Portfolio Management and currently focuses on debt and equity investments in the Life Science and Technology sectors. Michael joined Hercules Capital as an Analyst Intern in January 2007 and was promoted to the role of Associate in October 2009. He was promoted to Vice President in April 2011 and then to Managing Director, Portfolio Management in January 2019. Prior to Hercules, he held positions with Credit Suisse HOLT as an equity research analyst and with Bristol-Myers Squibb as a global sourcing and supplier management analyst. Michael graduated from Northeastern University with a B.S. in finance.

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Tom Hertzberg is a Managing Director responsible for business development in the life sciences and broader healthcare market, including sourcing and executing investment opportunities. Prior to joining Hercules Capital, Tom spent 15 years in a variety of roles at Silicon Valley Bank including sales and portfolio leadership positions. Most recently, Tom led a team within SVB’s Life Sciences and Healthcare practice, overseeing coverage of 24 states and 700 client relationships. Over his career, he has deployed several billion dollars of debt capital across a broad range of private and public technology and healthcare companies. He’s also a member of the Finance Committee for the Colorado Bioscience Association, which provides networking and development opportunities to professionals in Colorado’s thriving bioscience sector. Tom graduated with a BSBA from the University of Denver.

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Adam Soller is a Managing Director in the Life Sciences group working in the greater Washington, DC region. He has over 20 years of senior lending experience, with 17 of them in the life sciences industry. Prior to Hercules, Adam was a Managing Director at Oxford Finance. During his time at Oxford he originated, structured and underwrote nearly $3 billion in debt facilities for life sciences and healthcare companies. He was also responsible for originations in Australia, Europe, Israel and a majority of the United States. Prior to joining Oxford, Adam was an Analyst in the Acquisitions Group of Capital Automotive, a real estate investment trust, where he underwrote over $1 billion in transactions and managed a portion of a $2.5 billion portfolio. Adam holds a B.A. in economics and business, with a concentration in financial management from the Virginia Military Institute.

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Michael McMahon is a Director in Hercules Capital's Healthcare and Life Sciences group and is based in Boston. He focuses on deal origination, loan structuring, underwriting, and portfolio management with a broad range of private and public healthcare companies including innovative healthcare services, biotechnology, medical device, and other healthcare companies at all stages of development. Prior to joining Hercules in 2023, Michael spent 18 years in a variety of roles at Silicon Valley Bank with a focus on senior secured and mezzanine debt solutions. Over his career he led the structuring and underwriting of a variety of debt products across technology and healthcare: asset based and recurring revenue-based revolvers, venture debt term loans, mezzanine term loans, cash flow supported revolvers and term loans, and convertible debt. Michael graduated from Tufts University with a Bachelor of Arts in economics in 2003.

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Jeffrey Ralto joined Hercules in September 2021 and is a Principal in the Life Sciences Group working in the Boston office. From 2016 to 2021, Jeff was a Director and Vice President in the Healthcare Sponsor Finance group at Silicon Valley Bank where he underwrote and managed senior secured financings for private equity backed healthcare services and healthcare IT companies. Jeff was previously an Analyst and Associate at Hercules, supporting the Life Sciences and Technology groups.

Jeff graduated with honors from Northeastern University with a B.S. in Finance and is a CFA charterholder.

   

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John Miotti is a Principal in the Life Sciences Group working in the New York office. He underwrites investments to a broad range of healthcare companies, including biotechnology, healthtech, med device, and value-based care. John joined Hercules as an Analyst in January 2017 and was most recently promoted to Principal in January 2023. John graduated cum laude from Boston College with a B.A. in both Economics and English.    

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Brian Powers joined Hercules in 2023 and is a Principal responsible for business development, sourcing, and executing investment opportunities in the healthcare services and life sciences market. Prior to joining Hercules Capital, Brian spent 10 years in a variety of roles at Silicon Valley Bank, most recently as a Director within SVB’s Life Sciences and Healthcare practice, overseeing a team responsible for providing debt capital across a broad range of private and public technology and healthcare companies. Brian graduated from the University of Iowa with a B.S. in Finance and was a member of 2004 Co-Big 10 Champion Football Team. He is also a CFA charterholder.

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Katie Segien is a Vice President at Hercules Capital focusing on business development and investments in emerging growth-stage life science and healthcare companies. Since joining Hercules in 2008, Katie has worked across a broad range of life science and healthcare companies at various stages of growth.

Before joining Hercules, Katie held roles at Boston Children’s Hospital in their Innovation Accelerator, Credit Suisse, and Boston Scientific. Katie was a Flare Scholar at Flare Capital in 2018 and remains on their seed fund, Flare Scholar Ventures, providing pre-seed capital to healthcare-focused companies.

Katie received her MBA from the Kenan-Flagler School of Business at UNC-Chapel Hill and her BS in Finance at Northeastern University.

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John O’Leary joined Hercules in 2020 and is a Vice President working in the San Mateo office. John focuses on investment opportunities in public and private growth stage life sciences and healthcare companies within sectors that include healthcare technology, healthcare services, biotechnology, medical devices, and specialty pharmaceuticals.

Prior to Hercules, John worked in several roles at Silicon Valley Bank where he underwrote debt capital commitments to early and growth stage venture capital and private equity backed healthcare and technology companies.

John graduated from the University of California, Los Angeles with a B.A. in both Economics and French.

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Briana Gironda joined Hercules in 2020 and works on debt and equity transactions in the life sciences sector. While her primary focus is on clinical and commercial stage biotech companies, her investments also span medical device, health tech, and healthcare services.

Prior to joining Hercules, Briana was an associate at MidCap Financial, where she worked on the Leveraged Finance and Life Science teams underwriting transactions across a variety of industries.

Briana received a B.S. in Chemistry with a minor in Mathematics from William & Mary, where she was also an NCAA Division I gymnast.

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Alexandra Henderson is a Vice President in the Life Sciences Group at Hercules Capital working in the Boston office. Alexandra focuses on evaluating, structuring, and managing investments in both public and private growth-stage life sciences and healthcare companies across the biotechnology, specialty pharmaceuticals, medical device, and healthcare services sectors. Alexandra joined Hercules Capital in October 2020 and was most recently promoted to Vice President in July 2025. Prior to joining Hercules, Alexandra began her career at Santander Bank, where she completed a comprehensive credit training program with a focus on credit analysis, risk underwriting, and loan structuring. Alexandra graduated from the University of Notre Dame with a B.S. in both Science-Business and English and earned her CFA charter in July 2022.

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