Flexible, Responsive Capital
Life Science companies utilize debt financing solutions to accelerate or broaden the scope of their clinical development, invest in new R&D or commercial infrastructures, acquire external clinical assets, extend their cash runway past important value inflection points, or shore-up their balance sheets ahead of an IPO or negotiations with strategic partners. In this vertical, Hercules Capital focuses on the following sectors:
Drug Discovery, Drug Platform, Drug Delivery, Specialty Pharma, Life Sciences Tools, Medical Devices, and more.Work with us
LIFE SCIENCES TEAM
LIFE SCIENCES TEAM
Manuel A. Henriquez Founder, Chairman and CEO
Manuel is a 30-year veteran of the venture capital and financing community who has devoted his career to helping entrepreneurs and new businesses succeed by providing them with highly responsive, creative and flexible financing solutions.
As an entrepreneur and innovator himself, Manuel understands the challenges new ventures face as they seek to find the capital necessary to begin production, scale their operations or take their companies public. Under his leadership, Hercules has committed more than $7.3 billion in investments to over 410 VC-backed, innovative companies.
Prior to founding Hercules Capital, Manuel was a Managing Director at VantagePoint where he focused on technology investments. Prior to that, he served as President and Chief Investment Officer of Comdisco Ventures, a division of Comdisco, Inc.
As a long-standing advocate for children’s health, developmental learning and education, Manuel currently serves as a director on the following non-profit boards:
Northeastern University, where Manuel is a Member of the President West Coast Council, Member of the Academic Affairs and Student Experience Committee, and Member of the Corporation;
Lucile Packard Foundation for Children’s Health (LPFCH), which was established in 1996 out of the Packard Children’s Hospital at Stanford University and is an independent public charity, devoted exclusively to elevating the priority of children’s health and increasing the quality and accessibility of children’s healthcare through leadership and direct investment. Manuel serves as the Vice Chairman of the Board of Directors, Chairman of the Compensation Committee, Chairman of the Executive Search Committee, Member of the Executive Committee and Member of the Investment Committee.
Children’s Health Council “CHC” which specializes in working with children with ADHD, Learning Differences, Anxiety & Depression and Autism Spectrum Disorders and Teen Mental Health Therapy. Manuel serves as Corporate Treasurer, Chairman of the Finance Committee, Chairman of the Investment Committee and Member of the Executive Committee.
Previously, Manuel also served on the Board of Directors for the Charles Armstrong School, an independent, non-profit, co-educational lower- and middle-day school specializing in teaching students with language-based learning differences, such as dyslexia. Located in Belmont, California, Armstrong helps its students re-enter traditional public and private schools with the learning tools necessary to be language proficient.
R. Bryan Jadot Senior Managing Director
R. Bryan Jadot is a Senior managing director in the Life Sciences Group and brings over 18 years of financial and credit structuring experience. Prior to joining Hercules in 2005, Jadot served as vice president of the Life Sciences Group at Silicon Valley Bank (SVB) in Newton, MA where he co-managed a banking group dedicated to New England-based life science clients including biotechnology, medical device, and healthcare IT clients. Jadot also worked as the vice president of the Software Group at Silicon Valley Bank in Palo Alto, CA. Prior to Silicon Valley Bank, Jadot worked with the Corporate Banking arm of the Banque Nationale de Paris (BNP) in San Francisco, CA and was an assistant economist with the Department of Treasury’s Office of Eastern Europe and former Soviet Union in Washington DC. Jadot earned a B.A. in economics and government from California State University at Sacramento, and completed the Wells Fargo Bank Credit Management Training Program. He served as a nuclear operations specialist with the US Army (Europe) and is fluent in French.
Kristen Kosofsky Senior Managing Director
Kristen is a Senior Managing Director responsible for business development in the life sciences and broader healthcare market. Kristen is a seasoned executive, with more than 20 years of experience in the venture debt market focused on structuring financial transactions for biotechnology, medical device and other healthcare and cleantech related companies.
Most recently, Kristen served as Managing Director at Horizon Technology Finance. Prior to that Kristen served as Vice President, Life Sciences at Comerica Bank in Boston and co-lead the life sciences practice while more than doubling the assets under management in a two-year period. Before joining Coamerica, Kristen worked in a number of finance and business development roles at GATX Corporation and Transamerica Technology Finance.
Kristen received a Bachelor of Science in Business from Central Connecticut State University in New Britain, Connecticut.
Anup Arora Managing Director
Anup Arora is a Managing Director in the Life Science Group and brings to Hercules more than 14 years of operations, consulting, and investing experience in the healthcare industry. Before joining Hercules in 2013, Arora was with Easton Capital, where he was involved in numerous venture capital investments in biotechnology, medical device, diagnostics, and healthcare IT companies. During his tenure with Easton, Arora was also actively engaged in the strategic and operational management of several of his portfolio companies, including Bluebird Bio (FKA Genetix Pharmaceuticals) where he served as Chief Business Officer. Prior to Easton, Arora worked in global marketing at Pfizer, where he set clinical and marketing strategy for Celebrex and other products in the arthritis and pain area. Previously, Arora was a strategy consultant with Strategic Decisions Group, where he led engagements with life sciences companies in business development, R&D, marketing, and lifecycle management. Arora also spent two years engaged in biomedical research at Stanford Medical School. Arora holds an MBA with High Distinction (Baker Scholar) from Harvard Business School and dual bachelor’s degrees in Biology and Psychology from Stanford University.
Janice Bourque Managing Director
A managing director in the Life Sciences Group, Janice has more than 25 years of life science experience and focuses on emerging growth stage life science companies.
Before joining Hercules in 2010, Janice strategic corporate investor fundraising for Commons Capital and Oxford Bioscience Partners to create a global health fund focused on innovative healthcare investments for emerging and developing countries. Before that, she was Senior Vice President and group head-life sciences for Comerica. Janice also led the Massachusetts Biotechnology Council, the first biotechnology association in the world, for 12 years as President/CEO.
Janice also held several other senior managerial positions, including CFO/controller of Cambridge Medical Technology Corporation, senior public accountant for Coopers & Lybrand Emerging and Middle Market Group, and project manager for NASA Space Science at UNH.
She currently serves on the board of directors of the MIT Koch Institute for Integrative Cancer Research and The Village Bank, as an advisor to TBS Technologies, co-President of the Crystal Lake Conservancy and a member of the Women’s Forum. She has also been named as one of Boston Magazine’s 100 most influential women.
Janice holds an M.B.A in finance and accounting and Bachelor of Science in veterinary science from the University of New Hampshire.
Lake McGuire Managing Director
Lake McGuire is Managing Director responsible for business development in the life sciences and broader healthcare market. He is a seasoned executive, with more than 10 years of experience in the middle-market and venture debt markets, focused on structuring financial transactions for life sciences and technology related companies. Most recently, Mr. McGuire served as Vice President, Business Development at Comerica Bank, and was responsible for business development in the life sciences and technology markets. He has served in various roles in the Technology and Life Sciences and the Middle-Market Divisions during his 10-year tenure at Comerica Bank. Mr. McGuire received a Bachelor of Science in Construction Management from Michigan State University and a Master of Business Administration in Finance from the University of Michigan.
Nimesh Shah Managing Director
Nimesh Shah is a Managing Director in the Life Sciences Group. Mr. Shah brings to Hercules over 20 years of venture capital, Wall Street, and operating experience, with an emphasis on working with growth-oriented life science companies.
Prior to joining Hercules in 2018, Mr. Shah served as Chief Business Officer of Fractyl Labs, a clinical-stage company developing innovative technologies to address metabolic disease. Previously, Mr. Shah was a partner of Domain Associates, a leading health-care venture capital firm, and led that firm’s efforts in medical devices. During his time at Domain, Mr. Shah was involved with and served on the boards of a number of portfolio companies, including Twelve (acquired), Sequent Medical (acquired), Fractyl Labs, Zyga Technology (acquired), and Miramar Labs (acquired). Mr. Shah has also served in various roles at venture firm Cutlass Capital and investment bank Alex. Brown (now Deutsche Bank).
Mr. Shah received his Bachelor of Science in Biomedical Engineering from the Johns Hopkins University.
Himani Bhalla Principal
Himani Bhalla joined Hercules in June 2011 and is a Principal in the Life Sciences Group. Prior to Hercules, Bhalla was a financial analyst at Wells Fargo Bank where she was responsible for portfolio risk management. She has also worked as a finance analyst at hedge funds investing in US and global equities. Bhalla started her career in investment banking working with Religare Capital Markets and ICICI Bank, India’s largest private sector bank. Bhalla received a B.S. in Electronic Engineering from Delhi University, India and an M.B.A from the Management Development Institute, India. Bhalla is also a CFA® charterholder.
Charles Wehr Vice President
Charlie Wehr is a Vice President working in the Boston office, focused on a broad range of technology sectors, including enterprise software, digital media, information security, and life sciences, among others. Charlie comes to Hercules after nearly 6 years at Bridge Bank, where he was most recently a Vice President and Relationship Manager in the Technology Banking Division. Prior to that, Charlie was a Senior Consultant at Grant Thornton for 3 years.
Charlie received a B.A. in Public Policy Studies & Economics from Duke University, and a M.A. in Applied Economics from The John Hopkins University. He also holds a graduate certificate in Financial Management from The John Hopkins University, Carey Business School.
Michael Bowden Vice President
Michael joined Hercules Capital as an analyst intern in January 2007 and was promoted to the role of Associate in October 2009. In April 2011, Michael was promoted to Vice President and currently focuses on debt and equity investments in the Life Science and Technology sectors. Prior to Hercules, he held positions with Credit Suisse HOLT as an equity research analyst and with Bristol-Myers Squibb as a global sourcing and supplier management analyst.
Michael graduated from Northeastern University with a B.S. in Finance.
Featured Portfolio Companies
Anacor Pharmaceuticals, Inc.
Hercules Capital is a strong long-term partner for TransMedics. The Hercules team took the time to work with the management team to understand the business opportunity and challenges that we faced. They have used that knowledge to strategically support the company throughout its key stages of development. They are more than a venture debt lender, they are a business partner that focuses on helping their portfolio companies succeed and grow. TransMedics and I are fortunate to be working with the Hercules team.
Waleed Hassanein, M.D. (President & CEO, TransMedics )